Duke vs Virginia Prediction, Player Props & Odds (Oct 23, 2026)

Duke4-2 · 4-2 ATS

FINAL19 – 16

Virginia4-3 · 3-3-1 ATS

Final

Duke Blue Devils 19Virginia Cavaliers 16

Recap: Duke uses trick-play TD pass from Nate Sheppard to pull out 19-16 victory over Virginia (ESPN)

Table of Contents

Highlights

Full box score and play-by-play on ESPN

StatsBench picks

No StatsBench pick posted for this game. Today’s posted picks are graded live.

Pre-game preview

College Football · Friday, October 23, 2026 · 7:00 PM ET

Team	Moneyline	Spread	Total
Duke Blue Devils	–	–	–
Virginia Cavaliers	–	–	–

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Duke vs Virginia preview

Duke visits Virginia on Friday, October 23, 2026, at 7:00 PM ET. Virginia is a 2.5-point favorite with the total at 47.5, and the moneyline is Duke +120 to Virginia -122. The last meeting went to Duke, 27-20 on the road on December 6, 2025, and Duke is 1-2 in the last three head-to-head meetings but 1-0 against the spread in that span.

Duke is 4-2 straight up and 4-2 against the spread this season, with a 7-3 mark and 6-2 ATS over its last 10; most recently it lost 20-24 to North Carolina on October 17. Virginia is 4-3 and 3-3-1 ATS this season, 6-4 and 4-4-1 ATS over its last 10, and most recently lost 13-23 at SMU on October 17.

The most useful defensive split is on the ground: Duke allows 93.3 rushing yards per game (rank 18), while Virginia allows 152.7 (rank 85). Duke also allows 16 points per game (rank 17) compared with Virginia’s 19.7 (rank 38). On the prop side, Nate Sheppard’s anytime touchdown at -250 has cleared in 9 of his last 10.

Top Duke vs Virginia player props

The prop board for this game isn’t posted yet. It fills in as books open their lines.

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Records

Team	Record	ATS	O/U	Home	Away
Duke	4-2	4-2	3-3	3-1	1-1
Virginia	4-3	3-3-1	3-4	4-1	0-2

This season, regular season. ATS and O/U against each game’s closing line.

Duke vs Virginia head-to-head

Duke are 1-2, 1-0 ATS, O/U 0-1 in the last 3 meetings. Last time: Duke won 27-20 on December 6, 2025.

Date	Venue	Duke result	ATS	O/U
Dec 6, 25	Virginia home	W 27-20	W +3.5	U 58.5
Nov 15, 25	Duke home	L 17-34	–	–
Nov 18, 23	Virginia home	L 27-30	–	–

Recent form

Duke Blue Devils: last 10 (7-3, 6-2 ATS, O/U 4-4)

Date	Opponent	Result	ATS	O/U
Oct 17, 26	vs UNC	L 20-24	L -3	U 46.5
Oct 10, 26	@ GT	L 25-28	L -4.5	O 45.5
Sep 26, 26	vs W&M	W 62-7	W -43.5	O 61.5
Sep 19, 26	vs STAN	W 35-7	W -9.5	U 51.5
Sep 12, 26	@ ILL	W 31-27	W +6	O 51.5
Sep 5, 26	vs TULN	W 17-3	W -9.5	U 51.5
Dec 6, 25	@ UVA	W 27-20	W +3.5	U 58.5
Nov 29, 25	vs WAKE	W 49-32	W -2.5	O 53.5
Nov 22, 25	@ UNC	W 32-25	–	–
Nov 15, 25	vs UVA	L 17-34	–	–

Virginia Cavaliers: last 10 (6-4, 4-4-1 ATS, O/U 3-6)

Date	Opponent	Result	ATS	O/U
Oct 17, 26	@ SMU	L 13-23	P +10	U 51.5
Oct 10, 26	vs SYR	W 28-25	L -14	O 49.5
Oct 3, 26	@ FSU	L 7-38	L -1.5	U 51.5
Sep 26, 26	vs DEL	W 42-3	W -19.5	U 52.5
Sep 19, 26	vs WVU	L 27-38	L -10.5	O 51.5
Sep 11, 26	vs NORF	W 59-3	W -47.5	O 56.5
Aug 29, 26	vs NCSU	W 34-8	W -4	U 50.5
Dec 6, 25	vs DUKE	L 20-27	L -3.5	U 58.5
Nov 29, 25	vs VT	W 27-7	W -8.5	U 52.5
Nov 15, 25	@ DUKE	W 34-17	–	–

Injury report

No injuries listed for either team in our data as of 1:37 AM ET.

Matchup ranks

What each defense allows per game this season. Rank 1 allows the fewest, so a high number means a softer matchup for the other team’s overs.

	Duke defense	Virginia defense
Points allowed per game	16 (17th of 136)	19.7 (38th of 136)
Passing yards allowed per game	200.2 (54th of 136)	173.3 (24th of 136)
Rushing yards allowed per game	93.3 (18th of 136)	152.7 (85th of 136)
Total yards allowed per game	293.5 (20th of 136)	326 (41st of 136)